Incorporating biological knowledge into distance-based clustering analysis of microarray gene expression data
نویسندگان
چکیده
منابع مشابه
Incorporating biological knowledge into distance-based clustering analysis of microarray gene expression data
MOTIVATION Because co-expressed genes are likely to share the same biological function, cluster analysis of gene expression profiles has been applied for gene function discovery. Most existing clustering methods ignore known gene functions in the process of clustering. RESULTS To take advantage of accumulating gene functional annotations, we propose incorporating known gene functions into a n...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2006
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btl065